PROFUSE-S1 is a media supplement that significantly accelerates differentiation, fusion, and maturation rate of muscle progenitor cells with significantly shorter time to endpoint studies. PROFUSE-S1 can be used on various cells and media types including serum free media formulations
Differentiation Media (DM)
DM + PROFUSE-S1
Myotubes (α actinin) / Nuclei
PROFUSE-S1 enhances
bovine myoblast cells
differentiation
(48 hours post treatment)
Differentiation Media (DM)
DM + PROFUSE-S1
Myotubes (MyHC) / Nuclei
PROFUSE-S1 enhances
C2C12 differentiation
(72 hours post treatment)
PROFUSE-S1 enables the ability to:
- Conduct experiments in a timely manner, yielding faster research and development progress.
- Develop various muscle models in a flexible and efficient manner using different cell types and cells culture medias, in a timely manner, yielding faster research and development progress.
- Develop a muscle tissue model that better mimics natural muscle, allowing more accurate disease modeling.
- Engineer clinically relevant muscle tissue construct for regenerative medicine, in terms of protein profile and functionality.
- Achieve greater biomass production and higher protein levels.
Validated on primary myoblasts of various species (murine, bovine, ovine, porcine, avian, and piscine). Predicted to work on human cells.
Effective on immortalized myoblast cells including C2C12 cells, and on transdifferentiated fibroblasts.
Effective on myoblasts used for the generation of 3D engineered bioartificial muscles using scaffolds and various hydrogels.
Effective in serum-containing media as well as chemically defined serum free media formulations.
Expiry and storage conditions
- 3 years / -20°C, as powder
- 2 years / 4°C, as powder
- 1 year / -80°C, in solvent
- 6 months / -20°C, in solvent