Drug Discovery
We develop a pipeline of novel therapeutics and dietary supplements for skeletal muscle and metabolic health, enabled by a proprietary high-throughput human muscle platform with high translational relevance.
Muscle loss is a major challenge associated with a range of conditions, including GLP-1–based weight-loss drugs and aging (sarcopenia). Current discovery approaches rely on limited preclinical models, leading to poor clinical translatability. ProFuse is developing a pipeline of novel therapeutics and dietary supplements for muscle and metabolic health, enabled by the world’s first proprietary high-throughput human muscle platform designed to generate predictive, clinically relevant results.The platform integrates advanced functional readouts with physiologically relevant high throughput 2D and 3D human muscle models, representing a next-generation New Approach Methodology (NAM) for muscle-targeted drug discovery.
3D human Bioartificial Muscle (BAM) produced using ProFuse's proprietary technology
Fully mature human muscle with organized sarcomeres resulting in a superior in vitro disease modeling
Cultivated Meat
We are the muscle cultivation experts
We sell advanced muscle cell lines and muscle differentiation media supplements to enhance muscle growth, increase yield, accelerate production cycles, and reduce costs.
PROFUSE-S1, our differentiation media supplement, and PROFUSE-S8, our bovine muscle cell line, are now available for purchase.
PROFUSE-S1
Differentiation media supplement
PROFUSE-B8
A bovine muscle cell line
About Us
ProFuse is a biotechnology company focused on the discovery and development of first-in-class muscle therapeutics and dietary supplements for muscle and metabolic health. The company leverages a proprietary high-throughput human skeletal muscle platform to identify novel muscle-targeted compounds with strong clinical translatability.
Building on scientific breakthroughs from the Weizmann Institute of Science, ProFuse has further advanced its platform through years of dedicated research in human muscle biology, enabling predictive and physiologically relevant discovery in human muscle systems. The company is advancing its internal pipeline of therapeutics and dietary supplements while selectively engaging in strategic collaborations with pharmaceutical, biotechnology, nutraceutical, and academic partners.
The ProFuse team brings extensive expertise in skeletal muscle biology and drug discovery and development, combining deep scientific knowledge with industry experience. The company has received recognition and support from leading innovation bodies, including the Israel Innovation Authority and the European Union.
Latest News
Become Our Partner
We partner across the pharmaceutical, biotechnology, and dietary supplement sectors to advance the development of novel muscle therapeutics and dietary supplement products for muscle and metabolic health. Our collaboration model includes both ProFuse-originated programs and partner-originated programs, enabling joint advancement of drug and dietary supplement candidates through complementary capabilities.
In parallel, we collaborate with academic researchers to translate promising discoveries into therapeutic and nutritional programs, including the advancement of novel targets and externally generated hits.
If you are interested in exploring potential collaboration opportunities, we would be glad to connect.