ProFuse EIC
Transition Project
Revolutionary Tech for Efficient Muscle Tissue Growth in Cultivated Meat
Project Goal
The ProFuse EIC Transition project addresses the urgent need for sustainable meat alternatives by tackling key challenges in cultivated meat production—namely, improving muscle tissue growth, reducing costs, and enhancing product quality. This is vital as global meat demand is expected to double by 2050, while traditional meat production remains environmentally harmful and resource-intensive. Cultivated meat offers a safer, more sustainable solution that also mitigates risks from disease outbreaks. The project’s goal is to advance commercialization of the ProFuse products by refining muscle 3D growth methods, adapting the ProFuse cell lines to the customer’s production environment, and optimizing the ProFuse media supplements to maximize their positive impact on cost reduction and product quality improvement, ultimately supporting food security and ethical meat production.
The Global Challenge
With the global population projected to reach 10 billion by 2050, meat demand is expected to double. Traditional meat production methods are unsustainable due to limited resources and environmental impact. Cultivated meat offers a sustainable alternative, but current technologies face significant hurdles in cost, scalability, and quality.
Our
Technological Breakthrough
ProFuse introduces groundbreaking solutions
to overcome these challenges:
- Spontaneously Immortalized Myoblast Cell Line (PROFUSE-B8): This unique cell line is capable of both efficient proliferation and differentiation into muscle tissue.
- Muscle Differentiation Media Supplement (PROFUSE-S1 and S2): Our supplements enhance muscle stem cell fusion and maturation, significantly improving efficiency and reducing production time.
Key Benefits
Cost
Reducing expenses by up to 50% through increased biomass and protein content production
Efficiency
Achieves over 95% muscle cell fusion, increasing biomass yield by 150% and reducing operating costs by 50%.
Speed
reduce production cycles by up to 35%
Quality
Enhances protein content (4-5x higher) and improves texture and flavor.
Progress Overview So Far
Technical Achievements
- Adapted proprietary cell line PROFUSE-B8 to serum-free conditions with maintained differentiation in 2D and 3D.
- Demonstrated effective muscle growth on synthetic and edible scaffolds.
- Developed AI-based 3D image analysis for muscle fusion quantification.
- Continued optimization of PROFUSE-S2 supplements.
Safety & Regulatory
- Completed 90-day rat toxicity study for PROFUSE-S1 with no adverse effects.
- Confirmed supplement stability in digestive simulations.
- Developed LC-MS method for detecting supplement residues in cultured meat.
Business development and IP protection:
- Conducted in-depth analysis of the cultivated meat market to assess the potential market size and synergy with various stakeholders.
- Established the business model for each product family and business strategy in terms of go-to-market and partnership models.
- It secured new patents and created robust licensing models tailored to cultivated meat producers and the food industry
- Identified the various ecosystem partners, including suppliers and technology collaborators.
- Initiated customer POCS to demonstrate the technology benefits and impact on cost-saving
Communication & Outreach
- Active dissemination via LinkedIn, conferences, and educational programs.
- Implemented a robust data management system using cloud and ELM platforms
Communication Plan and Dissimination
ProFuse is committed to advancing the cultivated meat industry through strategic dissemination and collaboration with commercial partners, academia, regulators, and the public. Our outreach includes a strong web presence via our website, LinkedIn, and X, where we share scientific updates, events, and achievements. We actively publish and co-publish technical data, participate in and sponsor industry conferences, and contribute to scientific literature. Additionally, we engage in educational initiatives such as supporting academic courses and hosting tours to raise awareness and understanding of cultivated meat.
Please see the news section for a list of events attended, relevant news and other dissemination actions related to the project. Read more
Conclusion
The project is on track, with strong technical, regulatory, and market progress. ProFuse is aiming to begin commercialization in year two of the project
Our products ready for purchase
PROFUSE-S1
PROFUSE-S1 is a media supplement that significantly accelerates differentiation, fusion, and maturation rate of muscle progenitor cells with significantly shorter time to endpoint studies. PROFUSE-S1 can be used on various cells and media types including serum free media formulations.
PROFUSE-B8
PROFUSE-B8 is a pioneering spontaneously immortalized bovine myoblast cell line available for licensing. This innovative product is introducing a paradigm shift in the efficient cultivation of protein-rich muscle tissue.
Market Potential
Strategic Partnerships
- Target Market: Cultivated meat producers and media suppliers.
- Total available market size: $25 billion by 2050, with significant environmental benefits, Including a significant reduction millions of CO2 metric tons emissions annually.
We collaborate with leading companies in the cultivated meat industry to validate and optimize our technology.
Join us in transforming the future of meat production for a sustainable and efficient food system.
This project has received funding from the European Union’s Horizon Europe programme under the grant agreement No. 101158710
