About Us

At ProFuse, we are the skeletal muscle growth experts, developing innovative therapies for skeletal muscle loss and cultivated meat production

Advancing Muscle Growth & Innovation

Addressing the critical unmet need for effective drugs against muscle loss, ProFuse leverages its proprietary technological assets to efficiently and accurately discover novel muscle therapies. Our platform enables the high-throughput screening of thousands of compounds, identifying promising candidates with a high translational potential.

For the cultivated meat industry, we sell cutting-edge products, cell lines and differentiation media supplements to significantly reduce costs, enhance muscle growth, increase yield and accelerate production cycles. ProFuse actively collaborates with leading companies seamlessly integrating our products and knowhow into their production processes.

Our Journey & Breakthroughs

Founded in 2021, ProFuse licensed technology developed over six years of research at the Weizmann Institute of Science. Since then, we have achieved significant milestones, including winning first place in the 2021 Israel FoodTech Startup Competition and securing exclusive grants from both the European Innovation Council and the Israel Innovation Authority. We have launched two product lines and are actively supporting our cultivated meat customers in their scale-up efforts. We are particulary proud of our R&D team’s focus on skeletal muscle biology which is strengthened by the expertise of Professors Eldad Tzahor (Weizmann Institute of Science, Israel) and Professor. Shulamit Levenberg (Technion, Israel).

The Team

The company’s technology relies on 6 years of research conducted at the Weizmann Institute of Science, led by Professor Eldad Tzahor, a world-known expert in developmental biology and cardiac regeneration, and Dr. Tamar Eigler-Hirsh, an expert in muscle stem cell biology.

A great supporter of sustainability and veganism, and a seasoned entrepreneur with over 20 years of experience in start-ups growth and management in the fields of energy and consumer electronics. Guy grew startups from inception to exit as well as held management positions in global companies. He earned his B.Sc in International Business Management, Summa Cum Lauda.

Dr. Eigler-Hirsh characterized the molecular signaling pathway which is the basis of ProFuse Technology. She completed her doctoral degree at Cedars Sinai Medical Center in Los Angeles, and postdoctoral training under the mentorship of Prof. Eldad Tzahor at the Weizmann Institute of Science (WIS). Her research focuses on muscle development and regeneration, and the regulation of muscle progenitor cell differentiation and fusion.

Professor Tzahor is considered a world leader in the fields of myogenesis and cardiac development and regeneration. He joined the faculty of WIS in 2003 and serves as the Head of the Molecular Cell Biology Department. The Tzahor laboratory focuses on the development of novel therapeutic approaches by understanding the signaling mechanisms that regulate skeletal and cardiac muscle development and regeneration.

Ori brings to ProFuse extensive background in processes of cell-to-cell fusion as well as an expertise in multi-modal imaging techniques. He joined the faculty of the WIS in 2017. In his laboratory, he aims to cultivate a thorough understanding of membrane fusion and internalization processes, focusing on their contribution to the structure and function of muscles.

Joined ProFuse at 2021, Dr. Nuriel-Ohayon has over 18 years of experience in biological research, with technological expertise in cell culture and biochemical, immunological, and molecular biology techniques. She completed her Ph.D. in Medical Science at Bar-Ilan University, focusing on host-microbiota interactions under the mentorship of Prof. Omry Koren. Her postdoctoral studies at Bar-Ilan University explored the microbiome’s role in gestational diabetes mellitus. Later, as a lab manager and research associate in Dr. Shai Bel’s lab, she investigated the specialization of intestinal cells to understand how the intestine forms a barrier and why this barrier breaks down in inflammatory bowel diseases.

With over 15 years of international academic and industry experience, Dr. Sarig possesses a deep understanding of life sciences and tissue engineering. Motivated by a desire to innovate, she leads ProFuse’s efforts to explore new opportunities, partnerships, and breakthroughs in the field of muscle cultivation. Dr. Sarig holds a Ph.D. in Biotechnology & Food Engineering (Technion, Israel) and completed a post-doctoral fellowship in Material Science Engineering (NTU, Singapore).

Dr. Liat Lomnitski leverages her extensive experience in pharmaceutical development, gained at Teva and Perrigo, to bring a wealth of scientific expertise to ProFuse. Her background in Biochemistry (PhD, Bar Ilan University) and post-doctoral research in Neurobiochemistry (Tel Aviv University) complements this experience perfectly. Dr. Lomnitski’s certifications in Toxicology, GLP, GCP, Drug Registration, and Regulatory Affairs empower her to deliver comprehensive safety assessments across various product lines, including pharmaceuticals and novel foods.

Scientific Advisory Board

Professor Levenberg is a professor at the Biomedical Engineering Department at the Technion – Institute of Technology in Israel. Her discoveries relating to vascularization of stem cell-derived tissue constructs have been discussed in leading journals such as Nature-Biotechnology and PNAS, and have had significant impact on the scientific community. Professor Levenberg was selected by “Scientific American” as one of the world’s 50 leading scientists for her work in tissue engineering.

The Investors

The Partners

ProFuse Technology emerged from the IIA-backed FRESH START foodtech incubator program. After successfully graduating from the 24-month program, the company was awarded in 2023 a follow-on IIA grant to support further high-impact research.

In 2024, ProFuse Technology secured a prestigious €2.4 million EIC Transition Grant to accelerate cultivated meat production. This grant acknowledges ProFuse’s groundbreaking technology and its potential to reshape the cultivated meat industry

The ProFuse Technology stems from research conducted at the Weizmann Institute of Science in Israel, one of the world’s top-ranking multidisciplinary research institutions.